Kocka \u00ebsht\u00eb nj\u00eb ind i gjall\u00eb q\u00eb jo vet\u00ebm mb\u00ebshtet mekanikisht trupin, mbron organet vitale, si trurin, zemr\u00ebn, mushk\u00ebrit\u00eb por gjithashtu prodhon qelizat e gjakut, ruan mineralet dhe ndikon n\u00eb rregullimin e sistemit endokrin. <\/p>\n
Si rezultat i plakjes, ndotjes ambjentale, \u00e7ekuilibrimit hormonal, mungesave t\u00eb l\u00ebnd\u00ebve ushqyese, p\u00ebrdorimit t\u00eb shpesht\u00eb t\u00eb disa ila\u00e7eve, cikli i rimodelimit t\u00eb kockave mund t\u00eb \u00e7ekuilibrohet.<\/p>\n
Sipas statistikave t\u00eb fundit, shpesht\u00ebsia e osteoporoz\u00ebs n\u00eb qaf\u00ebn e femurit, n\u00eb shtyll\u00ebn kurrizore , ose t\u00eb dyja midis t\u00eb rriturve t\u00eb mosh\u00ebs 50 vje\u00e7 e lart \u00ebsht\u00eb 12.6%, nd\u00ebrsa prevalenca e densitetit t\u00eb ul\u00ebt t\u00eb kockave (dmth., Osteopenia, nj\u00eb pararend\u00ebse e osteoporoz\u00ebs) p\u00ebr t\u00eb nj\u00ebjt\u00ebn grupmosh\u00eb \u00ebsht\u00eb 43% . <\/p>\n
Degradimi i mas\u00ebs muskulore n\u00eb lidhje me mosh\u00ebn \u00ebsht\u00eb nj\u00eb proces i vazhduesh\u00ebm, dhe disa studime tregojn\u00eb nj\u00eb ulje t\u00eb mas\u00ebs s\u00eb muskujve duke filluar q\u00eb nga mosha 30 vje\u00e7.<\/p>\n
Nd\u00ebrsa osteoporoza karakterizohet nga mas\u00eb e ul\u00ebt kockore dhe p\u00ebrkeq\u00ebsim i indit t\u00eb kockave, sarkopenia \u00ebsht\u00eb nj\u00eb r\u00ebnie progresive t\u00eb mas\u00ebs muskulore me humbje t\u00eb forc\u00ebs ose performanc\u00ebs fizike. Provat n\u00eb rritje tregojn\u00eb se t\u00eb dy \u00e7rregullimet ndajn\u00eb shum\u00eb rrug\u00eb t\u00eb zakonshme biologjike.<\/p>\n
N\u00eb fakt, sindroma muskulo-skeletore e lidhur me mosh\u00ebn e quajtur “osteosarkopeni” thekson lidhjet patologjike midis \u00e7rregullimeve t\u00eb nj\u00ebkohshme t\u00eb kockave dhe muskujve. <\/p>\n
Osteosarcopenia karakterizohet nga kocka poroze dhe t\u00eb brishta, si dhe mas\u00eb dhe funksion i ul\u00ebt muskulor.<\/p>\n
Mitokondriet luan nj\u00eb rol thelb\u00ebsor n\u00eb sh\u00ebndetin e nj\u00ebsis\u00eb muskulo-kockore. <\/p>\n
Funksioni dhe sasia mitokondriale jan\u00eb t\u00eb r\u00ebnd\u00ebsishme n\u00eb mir\u00ebmbajtjen e osteoblasteve, osteoklasteve n\u00eb kocka dhe p\u00ebr funksionimin optimal t\u00eb miociteve n\u00eb muskuj. <\/p>\n
Shum\u00eb studime sot p\u00ebrqendrohen n\u00eb performanc\u00ebn mitokondriale, dhe \u00ebsht\u00eb pik\u00ebrisht mosfunksionimi mitokondrial q\u00eb d\u00ebmton osteogjenez\u00ebn, rrit aktivitetin e osteoklasteve dhe p\u00ebrshpejton plakjen e kock\u00ebs.<\/p>\n
Lidhur me plakjen e p\u00ebrgjithshme t\u00eb muskujve, mitokondrit\u00eb jan\u00eb rregullator\u00eb qendror\u00eb. <\/p>\n
N\u00eb m\u00ebnyr\u00eb t\u00eb ve\u00e7ant\u00eb, humbja e integritetit mitokondrial n\u00eb miocitet \u00ebsht\u00eb njohur si nj\u00eb faktor potencial n\u00eb degjenerimin e muskujve t\u00eb lidhur me mosh\u00ebn.<\/p>\n
Dy jan\u00eb faktor\u00ebt kryesor q\u00eb ndikojn\u00eb n\u00eb sh\u00ebndetin funksionin mitokondrial: oksigjeni O2 dhe acidi piruvik.<\/p>\n
Cil\u00ebsia e performanc\u00ebs mitokondriale \u00ebsht\u00eb nj\u00eb p\u00ebrb\u00ebr\u00ebs kryesor i plakjes. <\/p>\n
Qelizat e vjet\u00ebruara grumbullojn\u00eb mitokondri jofunksionale, duke rritur prodhimin e llojeve reaktive t\u00eb oksigjenit, p\u00ebr pasoj\u00eb duke shtuar mbetjet toksike n\u00eb qeliza, inde.<\/p>\n
Zbatime klinike.<\/p>\n
Strategjit\u00eb e trajtimit t\u00eb m\u00ebnyr\u00ebs s\u00eb jetes\u00ebs ndihmojn\u00eb n\u00eb mb\u00ebshtetjen e sh\u00ebndetit muskuloskeletor. <\/p>\n
????Studimet k\u00ebrkimore sugjerojn\u00eb q\u00eb nj\u00eb diet\u00eb anti-inflamatore, ushtrime si dhe suplemente t\u00eb tilla si acide yndyrore omega-3 dhe probiotik\u00eb mund t\u00eb ndikojn\u00eb pozitivisht n\u00eb dend\u00ebsin\u00eb dhe cil\u00ebsin\u00eb e kockave. <\/p>\n
????Qasjet terapeutike t\u00eb rekomanduara p\u00ebr pacient\u00ebt me sarkopeni p\u00ebrfshijn\u00eb nd\u00ebrhyrje t\u00eb p\u00ebrshtatshme ushtruese q\u00eb ndihmojn\u00eb n\u00eb zbutjen e humbjes s\u00eb muskujve dhe rind\u00ebrtimin e mas\u00ebs muskulore. <\/p>\n
????Komponent\u00eb shtes\u00eb t\u00eb trajtimit q\u00eb rrisin forc\u00ebn e muskujve mund t\u00eb p\u00ebrfshijn\u00eb proteina esenciale, vitamina, acide yndyrore, oksigjenoterapi.<\/p>\n
????Identifikimi i mosfunksionit mitokondrial dhe rritja e sh\u00ebndetit t\u00eb mitokondris\u00eb p\u00ebrmes trajtimeve t\u00eb m\u00ebnyr\u00ebs s\u00eb jetes\u00ebs mund t\u00eb ndihmojn\u00eb gjithashtu p\u00ebr t\u00eb adresuar \u00e7rregullimet e kockave dhe muskujve.<\/p>\n
Planet ushqimore terapeutike si\u00e7 \u00ebsht\u00eb plani ushqimor mitokondrial, p\u00ebrdorin ushqimin p\u00ebr t\u00eb mb\u00ebshtetur biogjenez\u00ebn mitokondriale. <\/p>\n
Ushtrimet fizike jan\u00eb nj\u00eb tjet\u00ebr qasje terapeutike p\u00ebr t\u00eb mb\u00ebshtetur mitokondrin\u00eb, duke promovuar rritjen e p\u00ebrmbajtjes mitokondriale, duke p\u00ebrmir\u00ebsuar kapaciteti i frym\u00ebmarrjes s\u00eb secilit mitokondrion. <\/p>\n
Trajnimi i kombinuar mund t\u00eb rris\u00eb k\u00ebto p\u00ebrfitime duke forcuar performanc\u00ebn dhe cil\u00ebsin\u00eb e mitokondris\u00eb p\u00ebr t\u00eb ruajtur sh\u00ebndetin energjik dhe funksional t\u00eb muskujve t\u00eb skeletit.<\/p>\n
Pregatiti Dr Ilir Allkja<\/p>\n
Referencat<\/p>\n
1- Sarafrazi N, Wambogo EA, Shepherd JA. Osteoporoza ose masa e ul\u00ebt e kockave n\u00eb t\u00eb rriturit e moshuar: Shtetet e Bashkuara, 2017-2018. <\/p>\n
2- Qendrat p\u00ebr Kontrollin dhe Parandalimin e S\u00ebmundjeve, Qendra Komb\u00ebtare e Statistikave t\u00eb Sh\u00ebndetit. Botuar n\u00eb Mars 2021. <\/p>\n
3-https:\/\/www.cdc.gov\/nchs\/products\/databriefs\/db405.htm<\/p>\n
4- Wiedmer P, Jung T, Castro JP, etj. Sarkopenia – mekanizmat molekular\u00eb dhe pyetjet e hapura. Aging Res Rev. 2021; 65: 101200. doi: 10.1016 \/ j.arr.2020.101200<\/p>\n
5-Reginster JY, Beaudart C, Buckinx F, Bruy\u00e8re O. Osteoporoza dhe sarkopenia: dy s\u00ebmundje apo nj\u00eb? Nutr Metab Care. 2016; 19 (1): 31-36. doi: 10.1097 \/ MCO.0000000000000230<\/p>\n
6- Kirk B, Miller S, Zanker J, Duque G. Nj\u00eb udh\u00ebzues klinik p\u00ebr patofiziologjin\u00eb, diagnoz\u00ebn dhe trajtimin e osteosarkopenis\u00eb. Maturitas. 2020; 140: 27-33. doi: 10.1016 \/ j.maturitas.2020.05.012<\/p>\n","protected":false},"excerpt":{"rendered":"
Kocka \u00ebsht\u00eb nj\u00eb ind i gjall\u00eb q\u00eb jo vet\u00ebm mb\u00ebshtet mekanikisht trupin, mbron organet vitale, si trurin, zemr\u00ebn, mushk\u00ebrit\u00eb por gjithashtu prodhon qelizat e gjakut, ruan mineralet dhe ndikon n\u00eb rregullimin e sistemit endokrin. Si rezultat i plakjes, ndotjes ambjentale, \u00e7ekuilibrimit hormonal, mungesave t\u00eb l\u00ebnd\u00ebve ushqyese, p\u00ebrdorimit t\u00eb shpesht\u00eb t\u00eb disa ila\u00e7eve, cikli i rimodelimit […]<\/p>\n","protected":false},"author":2,"featured_media":55185,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[],"class_list":{"0":"post-55184","1":"post","2":"type-post","3":"status-publish","4":"format-standard","5":"has-post-thumbnail","7":"category-te-tjera"},"_links":{"self":[{"href":"https:\/\/neutrale.al\/index.php\/wp-json\/wp\/v2\/posts\/55184","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/neutrale.al\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/neutrale.al\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/neutrale.al\/index.php\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/neutrale.al\/index.php\/wp-json\/wp\/v2\/comments?post=55184"}],"version-history":[{"count":1,"href":"https:\/\/neutrale.al\/index.php\/wp-json\/wp\/v2\/posts\/55184\/revisions"}],"predecessor-version":[{"id":55186,"href":"https:\/\/neutrale.al\/index.php\/wp-json\/wp\/v2\/posts\/55184\/revisions\/55186"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/neutrale.al\/index.php\/wp-json\/wp\/v2\/media\/55185"}],"wp:attachment":[{"href":"https:\/\/neutrale.al\/index.php\/wp-json\/wp\/v2\/media?parent=55184"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/neutrale.al\/index.php\/wp-json\/wp\/v2\/categories?post=55184"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/neutrale.al\/index.php\/wp-json\/wp\/v2\/tags?post=55184"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}